A Conversation with Jack Scannell: The Intractable ‘Sociotechnical’ Problems of Drug Discovery and Development, Genetic Triumphalism and Predictive Validity

·Decoding Bio··

Jack is one of the sharpest thinkers on the pharmaceutical industry, with a talent for coining terms that then propagate among industry insiders and into wider tech circles. He coined Eroom’s Law in 2012, and has had a large impact by establishing predictive validity as the dominant variable in drug R&D productivity.In this interview we discuss:Whether the four original causes of Eroom’s Law still hold, and if we’ve seen a change in the trend.Why feeding AI with data from poor biological models ...

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