An idiot’s guide to lead optimisation for proteins

Home Posts Tags RSS Feed ♪ An idiot’s guide to lead optimisation for proteins 2026/05/08 Or, understanding the Cradle-1 pipeline. Lead optimisation is the step in drug design where you take a molecule that sort of works and try to make it actually work, and it’s arguably the step where most real-world design campaigns succeed or die. Due to the influence of a couple of my pals, I have recently become interested in using machine learning to do lead optimisation for proteins. Said pals