Label-Free Microrefractometry of Interfacial Processes Using Fluorescent Smart Coverslips

arXiv:2605.01472v1 Announce Type: cross Abstract: Molecular dipoles near interfaces emit highly directional radiation due to near-field interactions, making surface-bound fluorophores sensitive probes of local physicochemical changes. We introduce smart coverslips, stably coated with uniform, brightly fluorescent nanobead films, that exploit refractive-index-dependent emission shifts for sensitive micro-refractometry in small volumes. Supercritical-angle fluorescence refractometry uses single ba...