Ketamine is an anesthetic with growing popularity as an antidepressant. As an antidepressant, it’s quite impressive. When it works, it’s often within hours- a huge improvement over giving a suicidal person a pill that might work 6 weeks from now. And it has a decent success rate in people who have been failed by several other antidepressants and are thus most in need of a new option. The initial antidepressant protocols for ketamine called for a handful of uses over a few weeks. Scott Alexander ...