Reconstruction of glymphatic transport fields from subject-specific imaging data, with particular emphasis on cerebrospinal fluid flow and tracer conservation
A. Derya Bakiler, Michael J. Johnson, Michael R. A. Abdelmalik, Frimpong A. Baidoo, Andrew Badachhape, Ananth V. Annapragada, Thomas J. R. Hughes, Shaolie S. Hossain·ArXiv q-bio·Bio·
arXiv:2605.00730v1 Announce Type: cross Abstract: The reconstruction of physically valid transport fields from subject-specific imaging data is a fundamental challenge in image-based computational modeling due to measurement noise, modeling uncertainties and discretization errors. Without a methodology to construct models that faithfully reflect the underlying physics, mechanistic understanding of complex biological systems is inherently limited. In this work, we address this challenge in the gl...