In 2012, the era of deep learning AI got legs with the convolutional neural network (AlexNet) that won the ImageNet challenge. Those images were everyday objects, animals, and scenes, unrelated to health and medicine. Over 7 years ago, I wrote a review in Nature Medicine entitled High-Performance Medicine that summarized the remarkable progress being made for AI interpretation of medical images. Now virtually every type of medical images has undergone extensive assessment with AI, including X-ra...