STAT+: Scientists made mice with half a brain. Then they filled them with human organoids
For the last decade, scientists have been steadily getting better at growing “cerebral organoids,” miniature, three-dimensional brain-like structures, from human stem cells in the lab. Now, a group from Stanford University has found a way to advance their usefulness for studying brain development and disease — by instead growing them inside mice that have had large parts of their own brains genetically removed. Neuroscientists say these “neuro-chimeric” mice, whose brains are half-human — by v...
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