The Lowdown on Low-Dose Aspirin for Primary Prevention

It’s hard to turn around a medical myth, exemplified by the notion that low-dose aspirin is safe and effective in healthy adults for primary prevention of heart disease, especially in people aged 60 years and older. In 2018, 3 pivotal, very large randomized trials were published, consistently showing the risk of major bleeding exceeded the benefit of CV event reduction. Even though it has now been >7 years since these trials were published, a substantial proportion of people of advanced age are ...